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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1588558Generated: October 26, 2026

Phenethylamine → N-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamide

https://huagongshe.com/reaction/1588558

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
ReactantMethyl N-cyano-3-quinolinecarboximidateHCID 10058988—
SolventMethanolHCID 887—
ProductN-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamideHCID 1973457891%

Reaction Steps

Methyl N-cyano-3-quinolinecarboximidate (0.32 g, 1.5 mmol) was dissolved in methanol (3 ml), 2-phenylethylamine (0.20 g, 1.65 mmol) was added. The mixture was stirred at room temperature for 30 minutes. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether to give the title compound (0.41 g, 1.36 mmol, yield: 91%) as pale yellow crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05223508
Source datasetuspto-grants-1993_06
ORD IDord-902a59291b4c402f8b43a60933439fb5
Source noteuspto-grants-1993_06