HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine → N-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | Methyl N-cyano-3-quinolinecarboximidate | HCID 10058988 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-cyano-N'-(2-phenylethyl)-3-quinolinecarboximidamide | HCID 19734578 | 91% |
Reaction Steps
Methyl N-cyano-3-quinolinecarboximidate (0.32 g, 1.5 mmol) was dissolved in methanol (3 ml), 2-phenylethylamine (0.20 g, 1.65 mmol) was added. The mixture was stirred at room temperature for 30 minutes. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether to give the title compound (0.41 g, 1.36 mmol, yield: 91%) as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05223508 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-902a59291b4c402f8b43a60933439fb5 |
| Source note | uspto-grants-1993_06 |