Phosphorus oxychloride → 1-Pentyl-2-(2-morpholinophenyl)-1,3,3-trimethyl guanidine

Beteiligte Stoffe

Reaktionsschritte

Reaction of 3-pentyl-1,1,3-trimethylurea (7.5 g) in benzene (80 ml) with 4-(2-aminophenyl)morpholine (6.46 g) in benzene (30 ml) in the presence of phosphorus oxychloride (4.06 ml) for 45 hours at 70° C. gave 1-pentyl-2-(2-morpholinophenyl)-1,3,3-trimethyl guanidine (b.p. 98° C. at 1.5 mm Hg).

Herkunft & Nachweise