Methyl iodide → HCID 178503979, compound

HRID 1588625Notes

Reaction equation

HRID 1588625 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:13][C:14]([NH2:16])=[S:15])[CH2:3][S:2]1.[CH3:17]I>CC(C)=O>[CH3:17][S:15][C:14](=[NH:16])[NH:13][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[N:4]1[CH2:5][CH2:6][O:1][S:2][CH2:3]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 18952332HCID 18952332, compound

Product 1

HCID 178503979HCID 178503979, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 1-(2-thiamorpholinophenyl)thiourea (12.6 g), methyl iodide (7.1 g) and acetone (60 ml) was heated at 90°-95° C. for 21/2 hours. The solvent was removed by evaporation and the residue dried under vacuum (5 mm/Hg) to give 2-methyl-1-(2-thiamorpholinophenyl)-2-thiopseudourea hydroidide (m.p. 176°-177° C.).

Workup

  1. temperaturewas heated at 90°-95° C. for 21/2 hours
  2. customThe solvent was removed by evaporation
  3. customthe residue dried under vacuum (5 mm/Hg)

Sources & evidence

ORD record
ord-3145419d7b4a4cdab4a2f1d5824c2736
Source dataset
uspto-grants-1993_06
Patent number
US05223498

Reaction notes

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