Methyl isothiocyanate → HCID 18952274, compound

HRID 1588669Notes

Reaction equation

HRID 1588669 reaction equation
[CH3:1][C:2]1[C:7]([NH2:8])=[C:6]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH:5]=[CH:4][CH:3]=1.[CH3:15][N:16]=[C:17]=[S:18]>ClCCl>[CH3:15][NH:16][C:17]([NH:8][C:7]1[C:2]([CH3:1])=[CH:3][CH:4]=[CH:5][C:6]=1[N:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)=[S:18]

Participants

4

Reactant 2

HCID 11167Methyl isothiocyanateHCID 18952122HCID 18952122, compound

Product 1

HCID 18952274HCID 18952274, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Reaction of 6-methyl-2-morpholinoaniline (8.75 g) with methyl isothiocyanate (4.7 g) in dichloromethane (50 ml ) at room temperature for four days yielded N-methyl-N-'-(6-methyl-2-morpholinophenyl)thiourea (m.p. 182°-183° C.).

Sources & evidence

ORD record
ord-84d45c2ea91e42578bcacb44c7ab0457
Source dataset
uspto-grants-1993_06
Patent number
US05223498

Reaction notes

Loading…