Pyridinium chloride → HCID 54426455, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 7.7 g (0.0225 mole) of 3-(4-methoxy benzoyl) 2-ethyl 5-nitro benzothiophene and 35 g of pyridine hydrochloride are heated at 185° C. for 2.5 h. The mixture is cooled and taken up in 100 ml of water. The product is filtered off and washed on the filter with water and dried in a vacuum at a temperature of 50° C. After purification by chromatography on a column of silica (eluant: heptane/ethyl acetate 6/4), 5.6 g of 3-(4-hydroxy benzoyl) 2-ethyl 5-nitro benzothiophene are obtained.

Provenance & Evidence