Potassium Carbonate → HCID 19754880, compound

Participants

Reaction Steps

The reaction and workup were carried out in the same manner as for Example 21 using K2CO3 (576 mg, 4.17 mmol), 4-bromomethylbenzoic acid N-methyl-N-cyclohexyl amide (1.124 g, 3.62 mmol) and 3,4,5-trimethoxyphenol (648 mg, 3.52 mmol). The crude product was chromatographed on silica gel using mixtures of ethyl acetate and hexane as eluents to give the title compound as a crystalline solid that could be recrystallized from ethyl acetate and hexane, m. pt. 115.53° C. (DSC).

Provenance & Evidence