Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 4-Formylbenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | n-Cyclopentylcyclohexanamine | HCID 219797 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 4-Formylbenzoic acid | HCID 12088 | — |
반응 단계
The acid chloride of 4-carboxybenzaldehyde (7.0 g, 46.5 mmol) was prepared in the same manner as in Example 29 using thionyl chloride (3.5 mL) and dimethylformamide (0.34 mL) in benzene (250 mL). The amide was prepared from the acid chloride in the same manner and using the same workup procedure as in Example 29 using N-cyclohexyl-N-cyclopentyl amine (15.6 g, 93.1 mmol) in THF (150 mL) at 0° C. The crude product was suitable for use without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05223539 |
| 출처 데이터셋 | uspto-grants-1993_06 |
| ORD ID | ord-a872729bfc2f4169ba1c28cdba5a239d |
| 출처 메모 | uspto-grants-1993_06 |