HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-Benzyl-2-cyano-1-phenylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,3-Dibromopropanenitrile | HCID 107299 | — |
| Reactant | N-benzyl-N'-phenylethane-1,2-diamine | HCID 5302982 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Benzyl-2-cyano-1-phenylpiperazine | HCID 14998752 | — |
Reaction Steps
In a manner similar to Preparation 1, react N-phenyl-N'-(phenylmethyl)-1,2-ethanediamine (0.41 g, 1.8 mmol) with 2,3-dibromopropanenitrile (0.77 g, 3.6 mmol) in toluene (5 mL) with triethylamine (0.73 g, 0.72 mmol) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05223623 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-8fad394e4d8445bf8c33f6d69aaad1e4 |
| Source note | uspto-grants-1993_06 |