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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1588978Generated: November 5, 2026

4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide → 4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamine

https://huagongshe.com/reaction/1588978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998756—
ReactantAluminium lithium hydrideHCID 21226445—
Product4-(2-Methoxyphenyl)-1-(phenylmethyl)-2-piperazinemethanamineHCID 14998772—

Reaction Steps

In a manner similar to Preparation 2, react 4-(2-methoxyphenyl)-1-(phenylmethyl)-2-piperazinecarboxamide (4.0 g, 16.6 mmol) with lithium aluminum hydride (1.0 g, 26 mmol) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05223623
Source datasetuspto-grants-1993_06
ORD IDord-8ce9f9b2798f49fdac256f071dcdde57
Source noteuspto-grants-1993_06