HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(Methylsulfonyl)amino]benzoyl chloride → N-[[4-(3-Aminophenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(Methylsulfonyl)amino]benzoyl chloride | HCID 11791119 | — |
| Reactant | 4-(3-Aminophenyl)-1-(phenylmethyl)-2-piperazinemethanamine | HCID 14998789 | — |
| Product | N-[[4-(3-Aminophenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide | HCID 14998790 | — |
Reaction Steps
In a manner similar to Preparation 3, react 4-(3-aminophenyl)-1-(phenylmethyl)-2-piperazinemethanamine (4.8 g, 16 mmol) with 4-[(methylsulfonyl)amino]benzoyl chloride (3.8 g, 16 mmol) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05223623 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-61e0746fb92c41d8b78d1675b767144d |
| Source note | uspto-grants-1993_06 |