2-Chloro-N-(3,5-dichlorophenyl)acetamide → N-(3,5-Dichlorophenyl)-2-[[(3,4-dimethoxyphenyl)methyl]amino]acetamide

HRID 1588998Notes

Reaction equation

HRID 1588998 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:8]([Cl:13])[CH:7]=1)=[O:4].[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH2:24][NH2:25])[CH:19]=[CH:20][C:21]=1[O:22][CH3:23]>>[Cl:13][C:8]1[CH:7]=[C:6]([NH:5][C:3](=[O:4])[CH2:2][NH:25][CH2:24][C:18]2[CH:19]=[CH:20][C:21]([O:22][CH3:23])=[C:16]([O:15][CH3:14])[CH:17]=2)[CH:11]=[C:10]([Cl:12])[CH:9]=1

Participants

3

Reactant 2

HCID 365502-Chloro-N-(3,5-dichlorophenyl)acetamideHCID 79832Veratrylamine

Product 1

HCID 14998823N-(3,5-Dichlorophenyl)-2-[[(3,4-dimethoxyphenyl)methyl]amino]acetamide

Procedure

In a manner similar to Preparation 12, react 2-chloro-N-(3,5-dichlorophenyl)acetamide with (3,4-dimethoxyphenyl)methanamine to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 12

Sources & evidence

ORD record
ord-c281ba2e941d4c9e93d216fb0d3f8eb8
Source dataset
uspto-grants-1993_06
Patent number
US05223623

Reaction notes

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