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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15890Generated: October 30, 2026

Hexahydro-2-benzimidazolinone → 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-one

https://huagongshe.com/reaction/15890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexahydro-2-benzimidazolinoneHCID 101982—
Reactant5-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinolineHCID 57444355—
Product1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)octahydro-2H-benzimidazol-2-oneHCID 57478384100%

Reaction Steps

The title compound was prepared in 100% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 5-{4-[2-(3-iodophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and octahydro-2H-benzimidazol-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-3bfbd1b17bbe4621a78b5cf9dde86043
Source noteuspto-grants-2010_06