N-Benzyl-2-chloroethan-1-amine → N-(3,5-dimethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine

HRID 1589002Notes

Reaction equation

HRID 1589002 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:11])[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1.Cl[CH2:13][CH2:14][NH:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH3:10][O:9][C:7]1[CH:6]=[C:5]([NH:11][CH2:13][CH2:14][NH:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=1

Participants

3

Reactant 2

HCID 22713N-Benzyl-2-chloroethan-1-amineHCID 663013,5-Dimethoxyaniline

Product 1

HCID 19755034N-(3,5-dimethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine

Procedure

In a manner similar to Preparation 29, react 3,5-dimethoxybenzenamine with N-(2-chloroethyl)benzenemethanamine to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 29

Sources & evidence

ORD record
ord-e99dffcccce74aa2b0199a88d263d108
Source dataset
uspto-grants-1993_06
Patent number
US05223623

Reaction notes

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