HRID1589012

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1cc(Br)cc(N2CCN(Cc3ccc(OC)c(OC)c3)C(CN)C2)c1

HCID14998775

未命名化合物

HCID14998830

未命名化合物

PRODUCTS

生成物

结构：COc1cc(Br)cc(N2CCN(Cc3ccc(OC)c(OC)c3)C(CNS(=O)(=O)c3ccc(-n4ccnc4)cc3)C2)c1

HCID14998831

未命名化合物

PROCEDURE

实验过程

In a manner similar to Preparation 3, react 4-(3-bromo-5-methoxyphenyl)-1-[(3,4-dimethoxyphenyl)methyl]-2-piperazinemethanamine with 4-(1H-imidazol-1-yl)benzenesulfonyl chloride to obtain the title compound.

WORKUP

后处理

customIn a manner similar to Preparation 3

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7a4eaa9403374bbea5c680a491821ba9
来源数据集: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05223623
来源说明: uspto-grants-1993_06

反应 SMILES

[Br:1][C:2]1[CH:3]=[C:4]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[C:19]([O:25][CH3:26])[CH:18]=3)[CH:12]([CH2:27][NH2:28])[CH2:11]2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.[N:29]1([C:34]2[CH:39]=[CH:38][C:37]([S:40](Cl)(=[O:42])=[O:41])=[CH:36][CH:35]=2)[CH:33]=[CH:32][N:31]=[CH:30]1>>[Br:1][C:2]1[CH:3]=[C:4]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][C:17]3[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[C:19]([O:25][CH3:26])[CH:18]=3)[CH:12]([CH2:27][NH:28][S:40]([C:37]3[CH:38]=[CH:39][C:34]([N:29]4[CH:33]=[CH:32][N:31]=[CH:30]4)=[CH:35][CH:36]=3)(=[O:41])=[O:42])[CH2:11]2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1