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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1589020Generated: November 2, 2026

2,3-dibromo-N-(2-methoxyethyl)-N-(4-nitrophenyl)propanamide → 4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-(4-nitrophenyl)-1-(phenylmethyl)-2-piperazinecarboxamide

https://huagongshe.com/reaction/1589020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-dibromo-N-(2-methoxyethyl)-N-(4-nitrophenyl)propanamideHCID 14998836—
ReactantN-(4-Ethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamineHCID 14998837—
Product4-(4-Ethoxyphenyl)-N-(2-methoxyethyl)-N-(4-nitrophenyl)-1-(phenylmethyl)-2-piperazinecarboxamideHCID 14998838—

Reaction Steps

In a manner similar to Preparation 23, react N-(4-ethoxyphenyl)-N'-(phenylmethyl)-1,2-ethanediamine with 2,3-dibromo-N-(2-methoxyethyl)-N-(4-nitrophenyl)propanamide to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05223623
Source datasetuspto-grants-1993_06
ORD IDord-43d3b95de1e34575b395d1d0209e9231
Source noteuspto-grants-1993_06