HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(Methylsulfonyl)amino]-N-[[4-(3-methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]benzamide dihydrochloride → N-[[4-(3-Methoxyphenyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(Methylsulfonyl)amino]-N-[[4-(3-methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]benzamide dihydrochloride | HCID 19755021 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | N-[[4-(3-Methoxyphenyl)piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide dihydrochloride | HCID 19755012 | — |
Reaction Steps
In a manner similar to Example 1, react 4-[(methylsulfonyl)amino]-N-[[4-(3-methoxyphenyl)-1-(phenylmethyl)piperazin-2-yl]methyl]benzamide dihydrochloride (2.3 g, 4 mmol) with H2 over Pd(OH)2 (0.3 g) catalyst to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05223623 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-a4716a19d4d243a2bb7c9e6546084be6 |
| Source note | uspto-grants-1993_06 |