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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1589039Generated: October 30, 2026

4-[(Methylsulfonyl)amino]benzoyl chloride → N-[(1-Methyl-4-phenylpiperazin-2-yl)methyl]-4-[(methylsulfonyl)amino]benzamide

https://huagongshe.com/reaction/1589039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(Methylsulfonyl)amino]benzoyl chlorideHCID 11791119—
Reactant1-Methyl-4-phenyl-2-piperazinemethanamineHCID 14998783—
ProductN-[(1-Methyl-4-phenylpiperazin-2-yl)methyl]-4-[(methylsulfonyl)amino]benzamideHCID 14998865—

Reaction Steps

In a manner similar to preparation 3, react 1-methyl-4-phenyl-2-piperazinemethanamine with 4-[(methylsulfonyl)amino]benzoyl chloride to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05223623
Source datasetuspto-grants-1993_06
ORD IDord-081bdec4f52542cca6ba7bf782dc43da
Source noteuspto-grants-1993_06