4-Chlorobenzoyl chloride → 4-Chloro-N-[3-(4-phenyl-1H-imidazol-1-yl)propyl]-benzamide

HRID 1589180Notes

Reaction equation

HRID 1589180 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.BrC1C=CC(C([NH:18][CH2:19][CH2:20][CH2:21][N:22]2[CH:26]=[C:25]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[N:24]=[CH:23]2)=O)=CC=1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:18][CH2:19][CH2:20][CH2:21][N:22]2[CH:26]=[C:25]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[N:24]=[CH:23]2)=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 135889214-Bromo-N-[3-(4-phenyl-1H-imidazol-1-yl)propyl]benzamide

Product 1

HCID 135889204-Chloro-N-[3-(4-phenyl-1H-imidazol-1-yl)propyl]-benzamide

Procedure

When 4-chlorobenzoyl chloride was substituted for the 4-bromobenzyl chloride of Example 76, There was obtained the title compound, m.p. 103°-105° C.

Sources & evidence

ORD record
ord-78d410c08c194d87867233139a42635d
Source dataset
uspto-grants-1986_02
Patent number
US04568687

Reaction notes

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