4-Chlorobenzoyl chloride → HCID 20248345, compound

Participants

Reaction Steps

A mixture of 2.68 g. of 4-(1H-imidazol-1-yl)-butynamine, 20 ml. of 1N sodium hydroxide and 75 ml. of methylene chloride was stirred and 2.6 ml. of 4-chlorobenzoyl chloride was added. The mixture was stirred for 18 hours, 5 ml. of 1N sodium hydroxide was added and the layers were separated. The organic layer was washed with water, dried over magnesium sulfate and concentrated to obtain the desired compound.

Provenance & Evidence