HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 13577653, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline | HCID 12896817 | — |
| Product | HCID 13577653 | HCID 13577653 | — |
Reaction Steps
The 5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine intermediate of Formula IV is reacted in step (3) with acetic anhydride to provide the novel intermediate 1-acetyl-5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine of Formula V. The reaction is conducted by heating the reaction mixture, for example, using a steam bath.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04568750 |
| Source dataset | uspto-grants-1986_02 |
| ORD ID | ord-15ec66165d6b4cbe9d38c9aa94b1cf0f |
| Source note | uspto-grants-1986_02 |