Tert-Butyl hypochlorite → 1,1-Di(p-fluorophenyl)-3-chlorourea

HRID 1589264Notes

Reaction equation

HRID 1589264 reaction equation
[Cl:1]OC(C)(C)C.[F:7][C:8]1[CH:13]=[CH:12][C:11]([N:14]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[C:15]([NH2:17])=[O:16])=[CH:10][CH:9]=1>CO>[F:7][C:8]1[CH:13]=[CH:12][C:11]([N:14]([C:18]2[CH:23]=[CH:22][C:21]([F:24])=[CH:20][CH:19]=2)[C:15]([NH:17][Cl:1])=[O:16])=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 521297Tert-Butyl hypochloriteHCID 133624301,1-Di(p-fluorophenyl)urea

Product 1

HCID 201841521,1-Di(p-fluorophenyl)-3-chlorourea

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

t-Butyl hypochlorite (7.5 g, 0.070 mole) was added to 1,1-di(p-fluorophenyl)urea (17.5 g, 0.071 mole) in 440 ml methanol at 0°-5° and the mixture stirred for 1 hour at that temperature to produce a solution containing step (a) title product.

Workup

  1. customto produce a solution

Sources & evidence

ORD record
ord-fd6946cf2a0d4fd1a045f84ed9591337
Source dataset
uspto-grants-1986_02
Patent number
US04568748

Reaction notes

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