HuagongsheHuagongshe Chemistry Print Report · For research reference only
Xanthine → 8-Benzylamino-1,3-di-n-butyl-xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Xanthine | HCID 1188 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 1,3-Di-n-butyl-8-bromo Xanthine | HCID 10154489 | — |
| Product | 8-Benzylamino-1,3-di-n-butyl-xanthine | HCID 13621808 | — |
Reaction Steps
Heat together a mixture of one equivalent of 8-bromo-1,3-di-n-butyl-xanthine with three to four equivalents of benzylamine at 160°-180° C. until thin layer chromatography analysis shows that no starting xanthine remains. Cool. Triturate with ethanol and water to yield 8-benzylamino-1,3-di-n-butyl-xanthine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04569936 |
| Source dataset | uspto-grants-1986_02 |
| ORD ID | ord-7e53700e31d24806822d866a473b4bd0 |
| Source note | uspto-grants-1986_02 |