HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one → (S)-2-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one | HCID 14358392 | — |
| Reactant | 5-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinoline | HCID 57444355 | — |
| Product | (S)-2-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one | HCID 57463853 | 60% |
Reaction Steps
The title compound was prepared in 60% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 5-{4-[2-(3-iodophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and (S)-hexahydro-3H-pyrrolo[1,2-c]imidazol-3-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732600B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-686dc9ff95c04e63b80a57009946e0a3 |
| Source note | uspto-grants-2010_06 |