反应详情

To a solution of 1.79 g of 4-acetylaminobenzoic acid in 50 ml of dried pyridine, was added 3.1 g of DCC. The mixture was stirred for 30 minutes while being cooled in ice. After addition of 3.36 g of 4-amidino-2-benzoylphenol methanesulfonate, the mixture was further stirred overnight. The reaction mixture was removed of the insolubles and mixed with ethyl ether to obtain a colorless solid substance which on recrystallization from methanol yielded 0.9 g of colorless crystals of 4-amidino-2-benzoylphenyl 4-acetylaminobenzoate methanesulfonate.

1. temperaturewhile being cooled in ice
2. waitthe mixture was further stirred overnight
3. customThe reaction mixture was removed of the insolubles
4. additionmixed with ethyl ether
5. customto obtain a colorless solid substance which
6. customon recrystallization from methanol