HCID 70453189, compound → HCID 70453257, compound

HRID 1589581Notes

Reaction equation

HRID 1589581 reaction equation
[OH:1][CH:2]([CH2:11][C:12]1[CH:17]=[CH:16][C:15](OC)=[CH:14][CH:13]=1)[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].OC(CC1C=CC([Cl:37])=CC=1Cl)C(C1C=CC=CC=1)=O.OC(CC1C=CC(N(C)C)=CC=1)C(C1C=CC=CC=1)=O.OC(CC1C=CC(OC)=C(OC)C=1)C(C1C=CC=CC=1)=O.OC(CC1C=CC(N(CC)CC)=CC=1)C(C1C=CC=CC=1)=O.OC(CC1C=C(C)C(N(C)C)=CC=1)C(C1C=CC=CC=1)=O.OC(CC1C=C(Cl)C(N(C)C)=CC=1)C(C1C=CC=CC=1)=O.OC(CC1C=CC(Cl)=CC=1)C(C1C=CC=CC=1)=O.OC(CC1C=CC=CC=1OC)C(C1C=CC=CC=1)=O>>[OH:1][CH:2]([CH2:11][C:12]1[CH:17]=[C:16]([Cl:37])[CH:15]=[CH:14][CH:13]=1)[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4]

Participants

10

Reactant 9

HCID 70453189HCID 70453189, compoundHCID 70453192HCID 70453192, compoundHCID 70453193HCID 70453193, compoundHCID 70453230HCID 70453230, compoundHCID 70453267HCID 70453267, compoundHCID 70453296HCID 70453296, compound2×HCID 70453323HCID 70453323, compoundHCID 70487133HCID 70487133, compoundHCID 86740660HCID 86740660, compound

Product 1

HCID 70453257HCID 70453257, compound

Procedure

The following compounds were prepared in a similar manner: 2-hydroxy-β-(4-methoxyphenyl)-propiophenone of melting point 51°-54° C.; 2-hydroxy-β-(2,4-dichlorophenyl)-propiophenone of melting point 106° C.; 2-hydroxy-β-(4-dimethylaminophenyl)-propiophenone of melting point 69°-71° C.; 2-hydroxy-β-(3,4-dimethoxyphenyl)-propiophenone of melting point 84°-87° C.; 2-hydroxy-β-(4-dimethylaminophenyl)-propiophenone of melting point 62° C.; 2-hydroxy-β-(4-diethylaminophenyl)-propiophenone of melting point 49°-51° C.; 2-hydroxy-5-methyl-β-(4-dimethylaminophenyl)-propiophenone of melting point 90°-92° C. and 2-hydroxy-5-chloro-β-(4-dimethylaminophenyl)-propiophenone of melting point 99° C.; 2-hydroxy-β-(4-chlorophenyl)-propiophenone, C15H13ClO2 (260.72); oily: calculated: C: 69.10; H; 5.03; Cl: 13.60; found: C: 69.5; H: 5.4; Cl: 13.2; and 2-hydroxy-β-(2-methoxyphenyl)-propiophenone, C16H16O3 (256.30); oily: calculated: C: 74.98; H: 6.29; found: C: 74.7; H: 6.4.

Workup

  1. customThe following compounds were prepared in a similar manner

Sources & evidence

ORD record
ord-74b043dd0f1c417dab03cbf478b02485
Source dataset
uspto-grants-1986_02
Patent number
US04571409

Reaction notes

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