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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1589631Generated: November 3, 2026

Dimethyl malonate → HCID 178437790, compound

https://huagongshe.com/reaction/1589631

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl malonateHCID 7943—
ReactantPropionamidine acetateHCID 12301254—
SolventSodium MethoxideHCID 10942334—
ProductHCID 178437790HCID 17843779089.5%

Reaction Steps

Using the procedure of Example 1, Part B1, 18.5 g (0.14 mole) of propionamidine acetate and 90 ml of 25% sodium methoxide were reacted with dimethyl malonate (0.14 mole) to provide 16.5 g (89.5%) of 4,6-dihydroxy-2-ethylpyrimidine according to Step (1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04572910
Source datasetuspto-grants-1986_02
ORD IDord-686f265e0aa44621adb79a3bf43494b7
Source noteuspto-grants-1986_02