Toluene → 4-(4-Chloromethylphenoxymethyl)-2-phenyloxazole

HRID 158967Notes

Reaction equation

HRID 158967 reaction equation
[CH3:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[S:22]([Cl:23])([Cl:24])=[O:25].[c:1]1(-[c:7]2[o:8][cH:9][c:10]([CH2:12][O:13][c:14]3[cH:15][cH:16][c:17]([CH2:18][OH:19])[cH:20][cH:21]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[o:8][cH:9][c:10]([CH2:12][O:13][c:14]3[cH:15][cH:16][c:17]([CH2:18][Cl:24])[cH:20][cH:21]3)[n:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 24386Thionyl ChlorideHCID 230248884-(2-Phenyl-4-oxazolylmethoxy)benzylalcohol

Product 1

HCID 230219114-(4-Chloromethylphenoxymethyl)-2-phenyloxazole

Sources & evidence

ORD record
ord-e1cfca706a1245b7829ebeb749864085
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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