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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1589736Generated: October 31, 2026

Hydrochloric Acid → 4-Fluorobenzimidate hydrogen chloride

https://huagongshe.com/reaction/1589736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
Reactant4-FluorobenzonitrileHCID 14517—
Product4-Fluorobenzimidate hydrogen chlorideHCID 178479546—

Reaction Steps

In anhydrous ethanol, compound [I'], commercially available 4-fluorobenzonitrile is reacted with gaseous hydrogen chloride to yield compound [J'], 4-fluorobenzimidate hydrogen chloride. Compound [J'] is reacted with gaseous ammonia to yield compound [K'], 4-fluorobenzamidine hydrogen chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05200110
Source datasetuspto-grants-1993_04
ORD IDord-080e02e70b1340468323dfe62a6de0f6
Source noteuspto-grants-1993_04