反应详情

114 g (0.49 mol) of 4-(trans-4'-propylcyclohexyl) benzyl alcohol was dissolved in 107 cm3 (1.05 mol) of SOCl2 and the solution was refluxed over a warm water bath for 5 hours. The excess SOCl2 was distilled off under reduced pressure and the residue was washed with 10% hydrochloric acid and water. The chloroform was distilled off under reduced pressure and the residue was distilled under reduced pressure (147° C./3.0 mmHg) to yield 114 g (0.45 mol) of 4-(trans-4'-propylcyclohexyl)-benzyl chloride.

1. temperaturethe solution was refluxed over a warm water bath for 5 hours
2. distillationThe excess SOCl2 was distilled off under reduced pressure
3. washthe residue was washed with 10% hydrochloric acid and water
4. distillationThe chloroform was distilled off under reduced pressure
5. distillationthe residue was distilled under reduced pressure (147° C./3.0 mmHg)