Ammonia → 4-Bromobenzene-1-carboximidamide--hydrogen chloride (1/1)

HRID 1589746Notes

Reaction equation

HRID 1589746 reaction equation
[ClH:1].[Br:2][C:3]1[CH:11]=[CH:10][C:6]([C:7](=[NH:9])O)=[CH:5][CH:4]=1.[NH3:12]>C(O)C>[ClH:1].[Br:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH2:12])=[NH:9])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 178479543HCID 178479543, compound

Product 1

HCID 122077144-Bromobenzene-1-carboximidamide--hydrogen chloride (1/1)

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

86 g (0.32) of 4-bromobenzimidate hydrogen chloride was added to 240 cm3 of ethanol saturated with gaseous ammonia and stirred at room temperature overnight. Approximately one-half of the volume of the ethanol was distilled off and the residual solution was recrystallized to yield 57 g (0.24 mol) of 4-bromobenzamidine hydrogen chloride.

Workup

  1. distillationApproximately one-half of the volume of the ethanol was distilled off
  2. customthe residual solution was recrystallized

Sources & evidence

ORD record
ord-ea9baaa758a34d4ea2013fca286c939f
Source dataset
uspto-grants-1993_04
Patent number
US05200110

Reaction notes

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