HCID 178443897, compound → HCID 178461181, compound

HRID 1589751Notes

Reaction equation

HRID 1589751 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C@H:21]4[CH2:26][CH2:25][C@H:24]([CH2:27]C)[CH2:23][CH2:22]4)=[CH:17][CH:16]=3)=[CH:11][N:10]=2)=[CH:5][C:4]=1[F:29])#[N:2].C(C1C=CC(C2N=CC(C3C=CC([C@H]4CC[C@H](CCCCCC)CC4)=CC=3)=CN=2)=CC=1F)#N>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C@H:21]4[CH2:26][CH2:25][C@H:24]([CH3:27])[CH2:23][CH2:22]4)=[CH:17][CH:16]=3)=[CH:13][N:14]=2)=[CH:5][C:4]=1[F:29])#[N:2]

Participants

3

Reactant 2

HCID 178443897HCID 178443897, compoundHCID 178455708HCID 178455708, compound

Product 1

HCID 178461181HCID 178461181, compound

Procedure

2-(4'-cyano-3'-fluorophenyl)-5-[4'-(trans-4"-ethylcyclohexyl) phenyl] pyrimidine ##STR33## 2-(4'-cyano-3'-fluorophenyl)-5-[4'-(trans-4"-butylcyclohexyl) phenyl] pyrimidine ##STR34## 2-(4'-cyano-3'-fluorophenyl)-5-[4'-(trans-4"-pentylcyclohexyl) phenyl] pyrimidine ##STR35## 2-(4'-cyano-3'-fluorophenyl)-5-[4'-(trans-4"-hexylcyclohexyl) phenyl] pyrimidine

Sources & evidence

ORD record
ord-5358a4c361e841a886ecba15eeefcfd5
Source dataset
uspto-grants-1993_04
Patent number
US05200110

Reaction notes

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