HCID 178443898, compound → HCID 178461184, compound

HRID 1589755Notes

Reaction equation

[C:1]([C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10]2[N:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][C:19]([C@H:22]4[CH2:27][CH2:26][C@H:25]([CH2:28]C)[CH2:24][CH2:23]4)=[CH:18][CH:17]=3)=[CH:12][N:11]=2)=[CH:5][C:4]=1[F:30])#[N:2].C(C1C(F)=CC(C2N=CC(C3C=CC([C@H]4CC[C@H](CCCCCC)CC4)=CC=3)=CN=2)=CC=1F)#N>>[C:1]([C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10]2[N:11]=[CH:12][C:13]([C:16]3[CH:21]=[CH:20][C:19]([C@H:22]4[CH2:27][CH2:26][C@H:25]([CH3:28])[CH2:24][CH2:23]4)=[CH:18][CH:17]=3)=[CH:14][N:15]=2)=[CH:5][C:4]=1[F:30])#[N:2]

Participants

Reactant 2

HCID 178443898HCID 178443898, compound

HCID 178455711HCID 178455711, compound

Product 1

HCID 178461184HCID 178461184, compound

Procedure

2-(4'-cyano-3',5'-difluorophenyl)-5-[4'-(trans-4"-ethylcyclohexyl) phenyl] pyrimidine ##STR37## 2-(4'-cyano-3',5'-difluorophenyl)-5-[4'-(trans-4"-butylcyclohexyl) phenyl] pyrimidine ##STR38## 2-(4'-cyano-3',5'-difluorophenyl)-5-[4'-(trans-4"-pentylcyclohexyl) phenyl] pyrimidine ##STR39## 2-(4'-cyano-3',5'-difluorophenyl)-5-[4'-(trans-4"-hexylcyclohexyl) phenyl] pyrimidine

Sources & evidence

ORD record: ord-3420e32d84c3405e8d4d74e9e2eecb98
Source dataset: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05200110

Reaction notes

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