HCID 178443551, compound → HCID 178461182, compound

HRID 1589757Notes

Reaction equation

HRID 1589757 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[CH:12][C:11]([C:14]3[CH:19]=[CH:18][C:17]([C@H:20]4[CH2:25][CH2:24][C@H:23]([CH2:26]C)[CH2:22][CH2:21]4)=[CH:16][CH:15]=3)=[CH:10][N:9]=2)=[CH:4][CH:3]=1.FC1C=CC(C2N=CC(C3C=CC([C@H]4CC[C@H](CCCCCCC)CC4)=CC=3)=CN=2)=CC=1.FC1C=CC(C2N=CC(C3C=CC([C@H]4CC[C@H](CCCCCC)CC4)=CC=3)=CN=2)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[CH:10][C:11]([C:14]3[CH:19]=[CH:18][C:17]([C@H:20]4[CH2:25][CH2:24][C@H:23]([CH3:26])[CH2:22][CH2:21]4)=[CH:16][CH:15]=3)=[CH:12][N:13]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 178443551HCID 178443551, compoundHCID 178455709HCID 178455709, compound

Product 1

HCID 178461182HCID 178461182, compound

Procedure

2-(4'-fluorophenyl)-5-[4'-(trans-4"-ethylcyclohexyl)phenyl] pyrimidine ##STR41## 2-(4'-fluorophenyl)-5-[4'-(trans-4"-butylcyclohexyl)phenyl] pyrimidine ##STR42## 2-(4'-fluorophenyl)-5-[4'-(trans-4"-pentylcyclohexyl)phenyl] pyrimidine ##STR43## 2-(4'-fluorophenyl)-5-[4'-(trans-4"-hexylcyclohexyl)phenyl] pyrimidine 2-(4'-fluorophenyl)-5-[4'-(trans-4"-heptylcyclohexyl)phenyl] pyrimidine

Sources & evidence

ORD record
ord-80bb8a1d72b14a13a5e1af8c7317a6f3
Source dataset
uspto-grants-1993_04
Patent number
US05200110

Reaction notes

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