Lauric Acid → HCID 18650857, compound

Participants

Reaction Steps

After 18 hours methyl-α-D-glucopyranoside (64 g, 0.33 mol, prepared according to example 6), dodecanoic acid (90 g, 0.45 mol) and 6 g lipase were added. After additional 22 hours the enzyme was removed by filtration and the product was worked up by short path distillation according to example 1, yielding a crude product containing 84% 6-O-dodecanoyl-D-glucopyranoside 9% methyl-D-glucoside and 7% diesters Part of the product was purified by chromatography and the identity of the title compound (being a ca 1:1 mixture of the anomers) was confirmed by NMR spectroscopy.

Provenance & Evidence