HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Dimethylimidazolidin-2-one → 5,5-Dimethyl-1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Dimethylimidazolidin-2-one | HCID 232656 | — |
| Reactant | 5-{4-[2-(3-Iodophenyl)ethyl]-1-piperazinyl)2-methylquinoline | HCID 57444355 | — |
| Product | 5,5-Dimethyl-1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone | HCID 68432535 | 87% |
Reaction Steps
The title compound was prepared in 87% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 5-{4-[2-(3-iodophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and 4,4-dimethyl-2-imidazolidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732600B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-c90a14aeaf374b27854baff8c8be10fe |
| Source note | uspto-grants-2010_06 |