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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1589807Generated: October 26, 2026

Leucinamide hydrochloride → Isobutyl (4S)-4-isobutyl-5-oxo-2-imidazolidinepropanoate

https://huagongshe.com/reaction/1589807

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLeucinamide hydrochlorideHCID 2733199—
ReactantIsobutyl 4-oxobutanoateHCID 10464575—
ProductIsobutyl (4S)-4-isobutyl-5-oxo-2-imidazolidinepropanoateHCID 57259664—

Reaction Steps

L-Leucinamide hydrochloride (3.2 g, 19.2 mmol) and isobutyl 4-oxobutanoate (3 g, 18.96 mmol) were reacted together according to the procedure of example 5A to give the title compound, 1.7 g (33%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05200406
Source datasetuspto-grants-1993_04
ORD IDord-82afd3c832574553a3cde10a5a8fa0e6
Source noteuspto-grants-1993_04