1-(Triphenylphosphoranylidene)acetone → HCID 54118605, compound

HRID 1589982Notes

Reaction equation

HRID 1589982 reaction equation
C1(P(C2C=CC=CC=2)(C2C=CC=CC=2)=[CH:8][C:9](=[O:11])[CH3:10])C=CC=CC=1.[CH:24]([C:26]1[O:30][N:29]=[C:28]([CH:31]2[CH2:36][CH2:35][CH2:34][CH2:33][O:32]2)[CH:27]=1)=O>ClCCl>[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36][CH:31]1[C:28]1[CH:27]=[C:26]([CH:24]=[CH:8][C:9](=[O:11])[CH3:10])[O:30][N:29]=1

Participants

4

Reactant 2

HCID 150381-(Triphenylphosphoranylidene)acetoneHCID 14439318HCID 14439318, compound

Product 1

HCID 54118605HCID 54118605, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

47 g of 1-triphenylphosphoranylidene-2-propanone were dissolved in 50 ml of dichloromethane, and 27 g of 5-formyl-3-tetrahydropyran-2-ylisoxazole were added. The reaction mixture was stirred for 1 day at room temperature and then evaporated down, the residue being stirred in methyl tert-butyl ether. After the triphenylphosphine oxide has been separated off, 43 g of a yellow oil remained.

Workup

  1. customevaporated down
  2. stirringthe residue being stirred in methyl tert-butyl ether
  3. customAfter the triphenylphosphine oxide has been separated off

Sources & evidence

ORD record
ord-ada026d48e3b4b11a079476b132693ac
Source dataset
uspto-grants-1993_04
Patent number
US05201935

Reaction notes

Loading…