Dichloromethane → HCID 178509803, compound

Participants

Reaction Steps

Into a 3 l capacity three-necked flask were added pyridium chlorochromate (161.7 g, 0.75 mol) and dichloromethane(1,000 ml), followed by agitating these, adding a dichloromethane solution (800 ml) of 4-{trans-4'-(hydroxymethyl]cyclohexyl}benzonitrile(107.6 g, 0.5 mol) at 20° C., agitating these for 90 minutes while keeping the temperature at 20° C., adding diethyl ether (1,500 ml), decanting the supernatant, passing the supernatant through a Florisil (trademark of the Floridin Company) column, concentrating under reduced pressure to obtain the captioned compound (101.2 g). Its structure was confirmed according to NMR spectra.

Provenance & Evidence