Water → 2-(3-Benzyloxy-5-fluorophenyl)butane-1,2-diol

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Reaction Steps

Lithium aluminium hydride (0.345 g) was added to a solution of the ester so obtained in diethyl ether (70 ml) and the mixture was stirred at ambient temperature for 1 hour. Water (10 ml) was added dropwise and the mixture was filtered. The organic layer was dried (MgSO4) and evaporated to give optically active 2-(3-benzyloxy-5-fluorophenyl)butane-1,2-diol (2.2 g), as an oil.

Provenance & Evidence