2,6-Diisopropylphenyl isocyanate → HCID 19769928, compound

Participants

Reaction Steps

To 1.01 g (4.33 mmol) of 2-(3,4-methylenedioxybenzyl)hexylamine, was added 9.2 ml of a hexane solution (0.47 mmol/l) of 2,6-diisopropylphenyl isocyanate and stirred for 3 hours. The reaction solution was concentrated and then purified by silica gel column chromatography (developed with hexane/ethyl acetate=2/1) to obtain 1.13 g of 1-(2-(3,4-methylenedioxybenzyl)hexyl)-3-(2,6-diisopropylphenyl)urea as amorphous solid (yield: 60%).

Provenance & Evidence