2,6-Diisopropylphenyl isocyanate → HCID 19769913, compound

Participants

Reaction Steps

To 4.8 g (21.7 mmol) of (+)-2-(3,4-methylenedioxyphenyl)hexylamine ([α]D21 =+2.64°, c=0.957, in ethanol), was added 46 ml of a hexane solution (0.472 M) of 2,6-diisopropylphenyl isocyanate, and the mixture was stirred for one hour at room temperature. The precipitated crystals were collected by filtration and recrystallized from ethanol to obtain 2.89 g of (+)- 1-(2-(3,4-methylenedioxyphenyl)hexyl)-3-(2,6-diisopropylphenyl)urea (Yield: 31%).

Provenance & Evidence