Hydroxyamine hydrochloride → HCID 73509151, compound

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Reaction Steps

To a mechanically stirred solution of the title compound of Example E (21 g, 0.085 mol) in 450 ml of pyridine was added hydroxylamine hydrochloride (8.83 g, 0.127 mol). After stirring for 4 days at room temperature the solution was concentrated in vacuo to give a solid which was chromatographed on silica gel eluting with 3% EtOH/CH2Cl2 to give the title compound (13.71 g, 61%) as a colorless powder: Anal calcd for C13H14N2O4 : C, 59.53; H, 5.40; N, 10.68. Found: C, 59.48; H, 5.47; N, 10.64. MS calcd for C13H14N2O4 262, found 262. DSC=153.2°-155.4° C. at 91.1 J/g.

Provenance & Evidence