Ethanethiol → HCID 86746713, compound

Participants

Reaction Steps

A solution of 1.3 g. (0.0022 mole) of 1,6-dihydro-2-[[(4-methoxyphenyl)methyl]thio]-4-methyl-6-(3-nitrophenyl)-1-[(4-nitrophenyl)carbonyl]-5pyrimidinecarboxylic acid, ethyl ester, 0.75 ml. (0.0097 mole) of trifluoroacetic acid and 0.32 g. (0.0050 mole) of ethanethiol in 15 ml. of dichloromethane is stirred at room temperature for 24 hours. The solvent is evaporated and the residue is triturated with isopropyl ether to give 0.95 . g of the title compound as a yellow solid, m.p. 139°-141°. TLC (silica gel; ethyl acetate:hexane, 1:1) Rf =0.35.

Provenance & Evidence