Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 3,4-Dichlorocinnamaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 2-Propen-1-ol, 3-(3,4-dichlorophenyl)- | HCID 53709191 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 3,4-Dichlorocinnamaldehyde | HCID 53880576 | 90.9% |
반응 단계
3-(3,4-Dichlorophenyl)prop-2-en-1-ol(1.0 g)(prepared by analogy to Example 2(i) and Example 1(ii)) was oxidised using the procedure of Swern (oxalyl chloride, 0.5 ml; dimethyl sulphoxide, 0.7 ml; triethylamine 3.4 ml) to give 3-(3,4-dichlorophenyl)-prop-2-enal (0.9 g). NMR 1H: 9.76(1H,d), 7.53(3H,m), 7.41(1H,d), 6.68(2H,dd).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05202356 |
| 출처 데이터셋 | uspto-grants-1993_04 |
| ORD ID | ord-e22a01a20a1441c9a3a8e29b56d70e80 |
| 출처 메모 | uspto-grants-1993_04 |