Dimethyl Sulfoxide → HCID 18651183, compound

Participants

Reaction Steps

The above alcohol (3.3 g) was oxidised using the conditions of Swern oxalyl chloride, 1.2 ml; dimethyl sulphoxide, 2.0 ml; triethylamine, 8.8 ml] in dichloromethane to give (±)-(2Z)-3-[trans-2-(3,4-dichlorophenyl)cyclopropyl]-2-fluoroprop-2-enal (3.25 g). NMR 1H: 9.20(1H,d), 7.39(1H,d), 7.22(1H,d), 6.95(1H,dd), 5.60(1H,dd), 2.20(2H,m), 1.50(2H,m).

Provenance & Evidence