Oxalic Acid → HCID 15107617, compound

HRID 1590442Notes

Reaction equation

HRID 1590442 reaction equation
[Cl:1][C:2]1[C:3]([CH3:12])=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5](O)([CH3:7])[CH3:6].C1(C)C=CC=CC=1.C(O)(=O)C(O)=O>O>[CH3:12][C:3]1[C:4]([C:5]([CH3:7])=[CH2:6])=[CH:9][CH:10]=[CH:11][C:2]=1[Cl:1]

Participants

5

Reactant 3

HCID 971Oxalic AcidHCID 1140TolueneHCID 15107612HCID 15107612, compound

Product 1

HCID 15107617HCID 15107617, compoundYield 53.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

190 g of 3-chloro-2-methyl-alpha,alpha-dimethylbenzyl alcohol are refluxed with 1.5 l of toluene and 370 g of oxalic acid under a water separator until no more water separates off. The oxalic acid is filtered off under suction and the filtrate is washed with sodium bicarbonate solution, dried over sodium sulfate and evaporated down. Fractional distillation of the residue gives 91.5 g of the desired compound, which is listed in Table 1 as Example 2.

Workup

  1. filtrationThe oxalic acid is filtered off under suction
  2. washthe filtrate is washed with sodium bicarbonate solution
  3. dry with materialdried over sodium sulfate
  4. customevaporated down
  5. distillationFractional distillation of the residue

Sources & evidence

ORD record
ord-95d4754067d3491c850dffd4371d8b18
Source dataset
uspto-grants-1993_04
Patent number
US05202503

Reaction notes

Loading…