Diethyl Carbonate → HCID 19767497, compound

Participants

Reaction Steps

A mixture of 2-cyclobutyl-2-hydroxymethylpropane-1,3-diol (6.7 g, 42 mmol), diethyl carbonate (5.5 g, 46 mmol) and potassium hydroxide (0.1 g in 5 ml dry ethanol) was heated to reflux under nitrogen for 15 minutes. Ethanol was then distilled off at atmospheric pressure and the residue distilled under reduced pressure. 3-Cyclobutyl-3-hydroxymethyloxetane was obtained as a colourless liquid (4.3 g, 73%) bp 130°-160° C. at 30 mm Hg.

Provenance & Evidence