2-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridine → N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamide

HRID 159064Notes

Reaction equation

HRID 159064 reaction equation
[CH:1]1([c:4]2[n:5][c:6]3[n:7]([cH:8][c:9]([N+:12]([O-:13])=[O:14])[cH:10][cH:11]3)[c:15]2[CH3:16])[CH2:2][CH2:3]1.[F:17][c:18]1[cH:19][c:20](-[c:27]2[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]2)[cH:21][cH:22][c:23]1[C:24](=[O:25])[OH:26]>>[CH:1]1([c:4]2[n:5][c:6]3[n:7]([cH:8][c:9]([NH:12][C:24]([c:23]4[c:18]([F:17])[cH:19][c:20](-[c:27]5[cH:28][cH:29][c:30]([C:33]([F:34])([F:35])[F:36])[cH:31][cH:32]5)[cH:21][cH:22]4)=[O:25])[cH:10][cH:11]3)[c:15]2[CH3:16])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 231205162-Cyclopropyl-3-methyl-6-nitroimidazo[1,2-a]pyridineHCID 231205273-Fluoro-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid

Product 1

HCID 23120536N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-fluoro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxamide

Sources & evidence

ORD record
ord-137294b9ce2841dfb727a168e7814ff3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…