Ethanol → HCID 19767972, compound

Participants

Reaction Steps

A mixture of ethyl 5,6,7,8-tetrahydro-7-(1H-imidazol-1-yl)-8-methylene-2-naphthalenecarboxylate (0.46 g), sodium hydroxide (0.8 g), ethanol (40 ml) and water (5 ml) is heated under reflux for 2 hours. The solution is evaporated, the residue is dissolved in water and the solution, acidified with acetic acid, is extracted with methylene chlorid. The organic layer is dried over sodium sulfate and evaporated to give 0.35 g of 5,6,7,8-tetrahydro-7-(1H-imidazol-1-yl)-8-methylene-2-naphthalenecarboxylic acid.

Provenance & Evidence