HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → L-Proline, 1-(1-oxo-3-phenylpropyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-(3-phenylpropionyl)-L-proline benzyl ester | HCID 45139423 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | L-Proline, 1-(1-oxo-3-phenylpropyl)- | HCID 10354601 | 100.9% |
Reaction Steps
10% Pd-C (3.00 g) was added to a 1% water-containing methanol solution (200 ml) of N-(3-phenylpropionyl)-L-proline benzyl ester (25.59 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 2.5 hours. After the catalyst was filtered off, the filtrate was concentrated to obtain 18.93 g of N-(3-phenylpropionyl)-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05204462 |
| Source dataset | uspto-grants-1993_04 |
| ORD ID | ord-45988458c08441e6ac6efc94489c5565 |
| Source note | uspto-grants-1993_04 |