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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1590808Generated: November 3, 2026

Water → L-Proline, 1-(1-oxo-3-phenylpropyl)-

https://huagongshe.com/reaction/1590808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantN-(3-phenylpropionyl)-L-proline benzyl esterHCID 45139423—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductL-Proline, 1-(1-oxo-3-phenylpropyl)-HCID 10354601100.9%

Reaction Steps

10% Pd-C (3.00 g) was added to a 1% water-containing methanol solution (200 ml) of N-(3-phenylpropionyl)-L-proline benzyl ester (25.59 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 2.5 hours. After the catalyst was filtered off, the filtrate was concentrated to obtain 18.93 g of N-(3-phenylpropionyl)-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05204462
Source datasetuspto-grants-1993_04
ORD IDord-45988458c08441e6ac6efc94489c5565
Source noteuspto-grants-1993_04